Search on: 15-OXOPROSTAGLANDIN 13-REDUCTASE 
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Descriptor English:   15-Oxoprostaglandin 13-Reductase 
Descriptor Spanish:   15-Oxoprostaglandina 13-Reductasa 
Descriptor Portuguese:   15-Oxoprostaglandina 13-Redutase 
Synonyms English:   Prostaglandin delta-13-Reductase
Prostaglandin-13,14-Reductase  
Tree Number:   D08.811.682.660.490
Definition English:   (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48. 
Indexing Annotation English:   DF: OXOPG REDUCTASE
History Note English:   94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was (NM) 1976-93; PROSTAGLANDIN DELTA 13 REDUCTASE was (NM) 1981-93 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   31899 
Unique Identifier:   D011452 

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